Yuval Nov's Webpage
Research Interests
- Biostatistics
- Stochastic methods in biotechnology
Publications
Refereed Journals
- Melamed Daniel, Nov Yuval, Malik Assaf, Yakass Michael B., Bolotin Evgeni, Shemer Revital, Hiadzi Edem K., Skorecki Karl L., and Livnat Adi (2021), "De novo mutation rates at the single-mutation resolution in a human HBB gene-region associated with adaptation and genetic disease." Forthcoming in Genome Research.
- Nov Yuval, Weiss Gideon, and Zhang Hanqin (2021), "Fluid Models of Parallel Service Systems under FCFS." Forthcoming in Operations Research.
- Beyar-Katz Ofrat, Lavi Noa, Ringelstein-Harlev Shimrit, Henig Israel, Yehudai-Ofir Dana, Haddad Nuhad, Fineman Riva, Ofran Yishai, Nov Yuval, Sahar Dvora, Moustafa-Hawash Nivin, Rowe Jacob M., and Zuckerman Tsila (2019), "Superior outcome of patients with favorable-risk acute myeloid leukemia using consolidation with autologous stem cell transplantation." Leukemia & lymphoma, 60(10), 2449-2456.
- Acevedo-Rocha Carlos G., Gamble Charles G., Lonsdale Richard, Li Aitao, Nett Nathalie, Hoebenreich Sabrina, Lingnau Julia B., Wirtz Cornelia, Fares Christophe, Hinrichs Heike, Mulholland Adrian J., Nov Yuval, Leys David, McLean Kirsty J., Munro Andrew W., and Reetz Manfred T. (2018), "P450-Catalyzed Regio- and Diastereoselective Steroid Hydroxylation: Efficient Directed Evolution Enabled by Mutability Landscaping." ACS Catalysis, 8(4), 3395-3410.
- Arad Ayala, Nammouz Shirin, Nov Yuval, Ohel Gonen, Bejar Jacob, and Vadasz Zahava (2017), "The Expression of Neuropilin-1 in Human placentas from Normal and Preeclamptic Pregnancies." International Journal of Gynecological Pathology, 36(1), 42-49.
- Acevedo-Rocha Carlos G., Reetz Manfred T., and Nov Yuval (2015), "Economical Analysis of Saturation Mutagenesis Experiments." Scientific Reports, 5:10654, DOI: 10.1038/srep10654.
- Rimar Doron, Nov Yuval, Rosner Itzhak, Slobodin Gleb, Rozenbaum Michael, Halasz Katy, Haj Tharwat, Jiries Nizar, Kaly Lisa, Boulman Nina, and Vadasz Zahava (2015), "Semaphorin 3A, an immunoregulator in Systemic Sclerosis." Rheumatology International, 35(10), 1625-1630.
- Ketter Katz Hadas, Lustig Avichai, Lev-Ari Tidhar, Nov Yuval, Rivlin Ehud, and Katzir Gadi (2015), "Eye Movements in Chameleons are not Truly Independent - Evidence from Simultaneous Monocular Tracking of Two Targets." The Journal of Experimental Biology, 218, 2097-2105.
- Goldberg Yair and Nov Yuval (2015), "Modeling and Optimization of Genetic Screens via RNA Interference and FACS." Probability in the Engineering and Informational Sciences, 29, 131-145.
- Nov Yuval (2014), "Probabilistic Methods in Directed Evolution: Library Size, Mutation Rate, and Diversity." In Ackerley D., Copp J., and Gillam E. (Eds), "Directed Evolution Library Creation: Methods and Protocols" (second edition), Methods in Molecular Biology, 1179, 261-278 Humana Press, Totowa.
- Rimar Doron, Rosner Itzhak, Nov Yuval, Slobodin Gleb, Rozenbaum Michael, Halasz Katy, Haj Tharwat, Jiries Nizar, Kaly Lisa, Boulman Nina, Daood Rula, Vadasz Zahava (2014), "Lysyl Oxidase is a Biomarker of Fibrosis in Systemic Sclerosis." Arthritis and Rheumatism, 66(3), 726-730.
- Blanghaps Nafna, Nov Yuval, and Weiss Gideon (2013), "Sojourn Time Estimation in an M/G/∞ Queue with Partial Information." Journal of Applied Probability, 50(4), 1044-1056.
- Nov Yuval, Fulton Alexander, and Jaeger Karl-Erich (2013), "Optimal Scanning of all Single-Point Mutants of a Protein." Journal of Computational Biology, 20(12), 990-997.
- Yehuda Guy, Barinova Sophia, Krugman Tamar, Pavlicek Tomas, Nov Yuval, and Nevo Eviatar (2013), "Microscale Adaptive Response of Charophytes of the Negev Desert, Israel: Species Divergences by AFLP." Natural Resources and Conservation, 1(3), 55-64.
- Nov Yuval and Segev Danny (2013), "Optimal Codon Randomization via Mathematical Programming." Journal of Theoretical Biology, 335, 147-152.
- Nov Yuval (2013), "Fitness Loss and Library Size Determination in Saturation Mutagenesis." PLoS ONE, 8(7): e68069. doi:10.1371/journal.pone.0068069
- Vadasz Zehava, Shasha-Lavsky Hadas, Nov Yuval, Bejar Jacob, Tadmor T, and Attias Dina (2013), "Wilms' tumor gene 1: a possible new proangiogenic factor in Hodgkin lymphoma." Applied Immunohistochemistry and Molecular Morphology, 21(2), 177-180.
- Davidov Ori, Nov Yuval (2012), "Improving an Estimator of Hsieh and Turnbull for the Binormal ROC Curve." Journal of Statistical Planning and Inference, 142, 872-877
- Nov Yuval (2012), "When Second Best is Good Enough: Another Probabilistic Look at Saturation Mutagenesis." Applied and Environmental Microbiology, 78(1), 258-262 [Supplemental Material]
- Brouk Moran, Nov Yuval, Fishman Ayelet (2010), "Improving Biocatalyst Performance by Integrating Statistical Methods into Protein Engineering." Applied and Environmental Microbiology, 76(19), 6397-6403
- Budowski-Tal Inbal, Nov Yuval, Kolodny Rachel (2010), "FragBag, an Accurate Representation of Protein Structure, Retrieves Structural Neighbors from the Entire PDB Quickly and Accurately." Proceedings of the National Academy of Sciences, 107(8), 3481-3486
- Nov Yuval, Davidov Ori (2010), "Minimum-Norm Estimation for a Bi-Exponential Survival Model." Statistics and Probability Letters, 80, 648-653
- Davidov Ori, Nov Yuval (2009), "Minimum-Norm Estimation for Binormal Receiver Operating Characteristic (ROC) Curves." Biometrical Journal, 51(6), 1030-1046
- Nov Yuval, Nov Oded (2008), "Living in a Bubble? Toward a Unified Bubble Theory." International Journal of General Systems, 37(5), 627-635
- Barak Yoram, Nov Yuval, Ackerley David, Matin AC (2008), "Enzyme Improvement in the Absence of Structural Knowledge: a Novel Statistical Approach." The ISME Journal, 2, 171-179 [Supplemental Material]
- Nov Yuval, Wein Lawrence (2005), "Modeling and Analysis of Protein Design Under Resource Constraints." Journal of Computational Biology, 12(2), 247-282
Refereed Conference Proceedings
- Vadasz Zehava, Shasha-Lavsky Hadas, Nov Yuval, Bejar Jacob, Attias Dina (2010), "Is WT-1 a New Pro-Angiogenic Marker in Hodgkin Lymphoma?" (abstract only). Acta Hematologica, 95(s4), s6. 8th International Symposium on Hodgkin Lymphoma
- Nov Yuval, Bassamboo Achal, Plambeck Erica (2006), "Optimal Pricing and Capacity Planning at Product Rollover" (6 pp. extended abstract). Proceedings of the MSOM (Manufacturing and Service Operations Management) Conference
Software
Toplib - Library Size Calculations for Saturation Mutagenesis.